Salt-inducible Kinase (SIK) Inhibitors

SIK1

SIK2

SIK3

Salt-inducible Kinase (SIK) Inhibitors

Product Name	SIK1	SIK2	SIK3	Purity
HG-9-91-01	SIK1	SIK2	SIK3	99.77%
YKL-05-099	SIK1		SIK3	99.76%
GLPG3312	SIK1, IC₅₀: 2.0 nM	SIK2, IC₅₀: 0.7 nM	SIK3, IC₅₀: 0.6 nM	98.63%
MRT199665	SIK1, IC₅₀: 110 nM	SIK2, IC₅₀: 12 nM	SIK3, IC₅₀: 43 nM	99.85%
SIK2/3-IN-2		SIK2, IC₅₀: 65 nM	SIK3, IC₅₀: 14 nM
SIK2/3-IN-3	SIK1, IC₅₀: 801 nM	SIK2, IC₅₀: 10.3 nM	SIK3, IC₅₀: 0.8 nM
ARN-3236	SIK1, IC₅₀: 21.63 nM	SIK2, IC₅₀: <1 nM	SIK3, IC₅₀: 6.63 nM	99.66%
YKL-06-061	SIK1			99.82%
Pterosin B			SIK3	99.98%
DB1113		SIK2	SIK3	99.86%
RSS0680		SIK2		98.03%
MRIA9	SIK1	SIK2	SIK3	98.88%
SIC-19		SIK2		98.00%
GLPG4970	SIK1, IC₅₀: 171 nM	SIK2, IC₅₀: 0.3 nM	SIK3, IC₅₀: 0.7 nM	99.60%
DB0614		SIK2
SK-124		SIK2	SIK3
SIK2-IN-4	SIK1, IC₅₀: 0.143 μM	SIK2, IC₅₀: 0.076 μM		99.06%
SIK2-IN-3	SIK1, IC₅₀: 0.128 μM	SIK2, IC₅₀: 0.084 μM
SIK2/3-IN-1		SIK2	SIK3
SIK1-IN-1	SIK1, IC₅₀: 0.7 nM	SIK2, IC₅₀: 75.3 nM	SIK3, IC₅₀: 240 nM

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